artículo académico

• Enhancement of octreotide antiproliferative activity by PEGylated PAMAM dendrimers delivery.  JOURNAL OF APPLIED POLYMER SCIENCE.  141(35). 2024
• A highly conserved plant volatile odorant receptor detects a sex pheromone component of the greater wax moth, Galleria mellonella (Lepidoptera: Pyralidae).  INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY.  163. 2023
• Cell internalization kinetics and surface charge accessibility of surface-modified PAMAM dendrimers.  ORGANIC & BIOMOLECULAR CHEMISTRY.  21(38):7782-7790. 2023
• Polyamidoamine dendrimers of the third generation-chlorin e6 nanoconjugates: Nontoxic hybrid polymers with photodynamic activity.  JOURNAL OF APPLIED POLYMER SCIENCE.  139(12). 2022
• Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Inhibition of the Glycine Receptor alpha 3 Function by Colchicine.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Mechanism-Based Rational Discovery and In Vitro Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity.  JOURNAL OF CHEMICAL INFORMATION AND MODELING.  60(6):3204-3213. 2020
• Modulation of glycine receptor single-channel conductance by intracellular phosphorylation.  SCIENTIFIC REPORTS.  10(1). 2020
• Polyamidoamine-based nanovector for the efficient delivery of methotrexate to U87 glioma cells.  NANOMEDICINE.  15(29):2771-2784. 2020
• Rational design and in vitro evaluation of novel peptides binding to neuroligin-1 for synaptic targeting.  JOURNAL OF CHEMICAL INFORMATION AND MODELING.  60(2):995-1004. 2020
• Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers.  JOURNAL OF CHEMICAL INFORMATION AND MODELING.  60(12):6634-6641. 2020
• Visible-light-responsive folate-conjugated titania and alumina nanotubes for photodynamic therapy applications.  JOURNAL OF MATERIALS SCIENCE.  55(16):6976-6991. 2020
• 17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-beta Toxicity by Nicotinic Acetylcholine Receptors.  JOURNAL OF ALZHEIMERS DISEASE.  67(1):343-356. 2019
• Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function.  FRONTIERS IN PHARMACOLOGY.  10. 2019
• Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors.  ACS CHEMICAL NEUROSCIENCE.  10(5):2551-2559. 2019
• Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers.  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE.  14(7):2227-2234. 2018
• P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of alzheimer´s disease.  NEUROPHARMACOLOGY.  128:366-378. 2018
• Partially PEGylated PAMAM dendrimers as solubility enhancers of Silybin.  PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY.  23(7):689-696. 2018
• Prevention of Synaptic Alterations and Neurotoxic Effects of PAMAM Dendrimers by Surface Functionalization.  NANOMATERIALS.  8(1):1-12. 2018
• Polyamido amine (PAMAM)-grafted magnetic nanotubes as emerging platforms for the delivery and sustained release of silibinin.  JOURNAL OF MATERIALS SCIENCE.  52(16):9269-9281. 2017
• ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of beta-amyloid peptide in hippocampal neurons.  NEUROPHARMACOLOGY.  100:116-123. 2016
• Functional modulation of glycine receptors by the alkaloid gelsemine.  BRITISH JOURNAL OF PHARMACOLOGY.  173(14):2263-2277. 2016
• Impact of mitichondrial dysfunction on neurodegenerative diseases: A key step on Alzheimer´s disease.  JOURNAL OF SYSTEMS AND INTEGRATIVE NEUROSCIENCE.  2(3):169-176. 2016
• Mechanism of PAMAM Dendrimers Internationalization in Hippocampal Neurons.  MOLECULAR PHARMACEUTICS.  13:3395-3403. 2016
• PAMAM-Conjugated Alumina Nanotubes as Novel Noncytotoxic Nanocarriers with Enhanced Drug Loading and Releasing Performances.  MACROMOLECULAR CHEMISTRY AND PHYSICS.  217:1712-1722. 2016
• PAMAM-grafted TiO2 nanotubes as novel versatile materials for drug delivery applications .  MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS.  65:164-171. 2016
• Reversal of Ethanol-Induced Intoxication by a Novel Modulator of Gß¿ Potentiation of Glycine Receptor.  JOURNAL OF BIOLOGICAL CHEMISTRY.  291:18791-18798. 2016
• Dendrimer nanocarriers drug action: perspective for neuronal pharmacology.  NEURAL REGENERATION RESEARCH.  10(7):1029-1030. 2015
• Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses.  PHARMACOLOGICAL RESEARCH.  101:18-29. 2015
• Evidence for a-helices in the large intracellular domain mediating modulation of the alpha 1 glycine receptor by ethanol and GBy.  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  352(1):148-155. 2015
• Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model.  JOURNAL OF ALZHEIMERS DISEASE.  42(1):143-155. 2014
• Inhibition of the Ethanol-induced Potentiation of a1 Glycine Receptor by a Small Peptide That Interferes with Gby Binding.  JOURNAL OF BIOLOGICAL CHEMISTRY.  287(48):40713-40721. 2012
• Synaptic Silencing and Plasma Membrane Dyshomeostasis induced by Amyloid-b peptide are Prevented by Aristotelia chilensis Enriched Extract.  JOURNAL OF ALZHEIMERS DISEASE.  31:879-889. 2012
• Inhibitory activities on Mammalian Central Nervous System Receptors and Computational Studies of Three Sesquiterpene lactones from Coraria ruscifolia subsp. Ruscifolia.  CHEMICAL & PHARMACEUTICAL BULLETIN.  59(2):161-165. 2011
• Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Slective Gbetagamma Modulation.  JOURNAL OF BIOLOGICAL CHEMISTRY.  285(39):30203-30213. 2010
• Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide that Interferes with Gbetasigma Binding.  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  331(3):933-939. 2009
• Inhibitory Effects of Tutin on Glycine Receptors in Spinal Neurons.  EUROPEAN JOURNAL OF PHARMACOLOGY.  559:61-64. 2007
• A Gby Stimulated Adenylyl Cyclase is Involved in Xenopus Laevis Oocyte Maturation.  JOURNAL OF CELLULAR PHYSIOLOGY.  202:223-229. 2005