artículo académico

• Unraveling the neuroprotective mechanisms of elephant black garlic extract against beta amyloid peptide-induced neurotoxicity.  FRONTIERS IN NUTRITION.  12. 2026
• Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide..  SCIENTIFIC REPORTS.  15(1). 2025
• The Alkaloid Gelsemine Reduces Aß Peptide Toxicity by Targeting Transglutaminase Type 2 Enzyme.  PLANTS-BASEL.  14(10). 2025
• Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  25(6). 2024
• Modulation of GABAA receptors and of GABAergic synapses by the natural alkaloid gelsemine.  FRONTIERS IN MOLECULAR NEUROSCIENCE.  15. 2023
• TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer's disease.  BIOMEDICINE & PHARMACOTHERAPY.  162. 2023
• Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24(3). 2023
• Antiseizure medication in early nervous system development. Ion channels and synaptic proteins as principal targets.  FRONTIERS IN PHARMACOLOGY.  13. 2022
• Modulatory Actions of the Glycine Receptor ß Subunit on the Positive Allosteric Modulation of Ethanol in a2 Containing Receptors.  FRONTIERS IN MOLECULAR NEUROSCIENCE.  14(18). 2021
• Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Inhibition of the Glycine Receptor alpha 3 Function by Colchicine.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Modulation of glycine receptor single-channel conductance by intracellular phosphorylation.  SCIENTIFIC REPORTS.  10(1). 2020
• Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers.  JOURNAL OF CHEMICAL INFORMATION AND MODELING.  60(12):6634-6641. 2020
• 17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-beta Toxicity by Nicotinic Acetylcholine Receptors.  JOURNAL OF ALZHEIMERS DISEASE.  67(1):343-356. 2019
• Data on SVCT2 transporter expression and localization in cancer cell lines and tissues.  DATA IN BRIEF.  25:1-25. 2019
• Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.  FREE RADICAL BIOLOGY AND MEDICINE.  135:283-292. 2019
• Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function.  FRONTIERS IN PHARMACOLOGY.  10. 2019
• Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors.  ACS CHEMICAL NEUROSCIENCE.  10(5):2551-2559. 2019
• Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain.  JOURNAL OF CLINICAL INVESTIGATION.  126(7):2547-2560. 2016
• A single phenylalanine residue in the main intracellular loop of a1 y-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol..  ANESTHESIOLOGY.  115(3):464-473. 2011
• Activated G protein as subunits increase the ethanol sensitivity of human glycine receptors..  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  339(2):386-393. 2011
• Allosteric modulation of retinal GABA receoptors by ascorbic acid.  JOURNAL OF NEUROSCIENCE.  31(26):9672-9682. 2011
• Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Slective Gbetagamma Modulation.  JOURNAL OF BIOLOGICAL CHEMISTRY.  285(39):30203-30213. 2010
• Effects of Pulp and Paper Mill Discharges on Caged Rainbow Trout (Oncorhynchus mykiss): Biomarker Responses Along a Pollution Gradient in the Biobio River, Chile.  ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY.  25(9):2280-2287. 2006
• Reproductive, Physiological, and Biochemical Rsponses in Juvenile Female Rainbow Trout (Oncorphynchus mykiss) Exposed to Sediment from Pulp and Paper Mill Industrial Discharge Areas.  ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY.  24(8):1935-1943. 2005