artículo académico

• Development of a cationic bionanocomplex from N-aryl-chitosan derivatives for controlled drug release.  CARBOHYDRATE POLYMERS.  380. 2026
• N-acetylcysteine Efficacy on Cocaine Base Paste Use Disorder: A Randomized Double-blind Placebo-controlled Clinical Trial.  JOURNAL OF ADDICTION MEDICINE.  1-9. 2025
• Health risk due to the chronic use of formaldehyde in workplace settings and as a component of hair straightening products.  HORIZONTE MEDICO.  24(2). 2024
• Multilayer Nanocarrier for the Codelivery of Interferons: A Promising Strategy for Biocompatible and Long-Acting Antiviral Treatment.  PHARMACEUTICS.  16(11). 2024
• Starches Isolated from Potatoes Grown in Chile: Characterisation and Nanoparticle Preparation.  POTATO RESEARCH.  67(4):1187-1207. 2024
• Development and optimization of teriflunomide-loaded chondroitin sulphate-coated nanostructured lipid carriers (NLCs) through box behnken design.  JOURNAL OF THE CHILEAN CHEMICAL SOCIETY.  68(2):5832-5838. 2023
• Evaluation of the Effects of Gamma Radiation Sterilization on Rhein-Loaded Biodegradable Microparticles for the Treatment of Osteoarthritis.  JOURNAL OF PHARMACEUTICAL SCIENCES.  112(3):837-843. 2023
• Intramuscularly Administered PLGA Microparticles for Sustained Release of Rivastigmine: In Vitro, In Vivo and Histological Evaluation.  JOURNAL OF PHARMACEUTICAL SCIENCES.  112(12):3175-3184. 2023
• Prototypes of nutraceutical products from microparticles loaded with stilbenes extracted from grape cane.  FOOD AND BIOPRODUCTS PROCESSING.  134:19-29. 2022
• Encapsulation of Phenolic Compounds from a Grape Cane Pilot-Plant Extract in Hydroxypropyl Beta-Cyclodextrin and Maltodextrin by Spray Drying.  ANTIOXIDANTS.  10(7). 2021
• Polymeric nanoencapsulation of alpha interferon increases drug bioavailability and induces a sustained antiviral response in vivo.  MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS.  116:1-6. 2020
• Optimization of rhein-loaded polymeric nanoparticles using a factorial design and evaluation of the cytotoxic and anti-inflammatory effects.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY.  44(8):1285-1294. 2018
• Development, characterization and in vitro evaluation of biodegradable rhein-loaded microparticles for treatment of osteoarthritis.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES.  96:390-397. 2017
• Oral Study of the Effect of Rosmarinus officinalis (Rosemary) Mouthrinse on Healing Wounds of the Oral Mucosa.  INTERNATIONAL JOURNAL OF ODONTOSTOMATOLOGY.  11(4):411-417. 2017
• Capreomycin oleate microparticles for intramuscular administration: preparation, in vitro release and preliminary in vivo evaluation.  JOURNAL OF CONTROLLED RELEASE.  209:229-237. 2015
• NP/HILIC-ELSD separation of phospholipid classes, application to preliminary analysis of plasma low density lipoproteins.  JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES.  38:243-250. 2015
• Quantitative Determination of Rivastigmine from a New Biodegradable Microparticulate System by High-Performance Thin-Layer Chromatography.  JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC.  28(3):251-255. 2015
• Desarrollo de nanopartículas biodegradables de capsaicina y evaluación de cesión del principio activo desde formulaciones semisolidas.  REVISTA DE FARMACOLOGÍA DE CHILE.  7(2):41-49. 2014
• Desarrollo de un carrier nanoparticulado como estrategía de transporte a traves del sistema nervioso central.  REVISTA DE FARMACOLOGÍA DE CHILE.  7(2):17-24. 2014
• Development and Characterization of PLGA Nanoparticles Loaded with Florfenicol.  LATIN AMERICAN JOURNAL OF PHARMACY.  33(7):1139-1143. 2014
• Nanopartículas poliméricas: Tecnología y aplicaciones farmaceuticas.  REVISTA DE FARMACOLOGÍA DE CHILE.  7(2):7-16. 2014
• Development of biodegradable methylprednisolone microparticles for treatment of articular pathology using a spray-drying technique.  INTERNATIONAL JOURNAL OF NANOMEDICINE.  8:2065-2076. 2013
• Successful factorial design for the optimization of methylprednisolone encapsulation in biodegradable nanoparticles.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY.  39(2):310-320. 2013
• Dexamethasone Acetate Encapsulation into Trojan Particles.  JOURNAL OF CONTROLLED RELEASE.  128(1):41-49. 2008
• Evaluating Average Bioequivalence Using Methods for High Variability Drugs: A Case Study.  JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS.  46. 2008
• Morphology, Structure and Supramolecular Organization of Hybrid 1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine-Hyaluronic Acid Microparticles Prepared by Spray Drying.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES.  34(1):12-21. 2008
• Supramolecular Organization and Release Properties of Phospholipid-Hyaluronan Microparticles Encapsulating Dexamethasone.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS.  70(1):116-126. 2008
• Encapsulation of Dexamethasone Into Biodegradable Polymeric Nanoparticles.  INTERNATIONAL JOURNAL OF PHARMACEUTICS.  331:153-159. 2007
• Method Validation for the Determination of Furosemide in Plasma by Liquid-Liquid Extrraction and High-Performance Liquid Chromatography with Fluorescence Detection.  JOURNAL OF THE CHILEAN CHEMICAL SOCIETY.  50(2):479-482. 2005
• Liquid Chromatographic Assay for Fast Determination of Simvastatin in Drug Substance.  JOURNAL OF THE CHILEAN CHEMICAL SOCIETY.  48(4):289-290. 2004