artículo académico

• Acrylamide and bisphenol A: two plastic additives increase platelet activation, via oxidative stress.  FRONTIERS IN PHARMACOLOGY.  16. 2025
• Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide..  SCIENTIFIC REPORTS.  15(1). 2025
• Chilean Phaseolus vulgaris landraces: A dietary source influencing NETs formation and phagocytic efficiency.  CELLULAR IMMUNOLOGY.  420-421. 2025
• In Silico Characterization of Gelsemium Compounds as Glycine Receptor Ligands.  COMPOUNDS.  5(4). 2025
• Phenotypic and molecular characterization of the exon 13-15 duplication in LDLR: Implications for familial hypercholesterolemia.  JOURNAL OF CLINICAL LIPIDOLOGY.  1-11. 2025
• The Alkaloid Gelsemine Reduces Aß Peptide Toxicity by Targeting Transglutaminase Type 2 Enzyme.  PLANTS-BASEL.  14(10). 2025
• Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  25(6). 2024
• Identification of Structural Determinants of the Transport of the Dehydroascorbic Acid Mediated by Glucose Transport GLUT1.  MOLECULES.  28(2). 2023
• Modulation of GABAA receptors and of GABAergic synapses by the natural alkaloid gelsemine.  FRONTIERS IN MOLECULAR NEUROSCIENCE.  15. 2023
• Neuroprotective Properties of Eudesmin on a Cellular Model of Amyloid-beta Peptide Toxicity.  JOURNAL OF ALZHEIMERS DISEASE.  94:S97-S108. 2023
• New Benzodihydrofuran Derivatives Alter the Amyloid beta Peptide Aggregation: Strategies To Develop New Anti-Alzheimer Drugs.  ACS CHEMICAL NEUROSCIENCE.  14(15):2590-2602. 2023
• TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer's disease.  BIOMEDICINE & PHARMACOTHERAPY.  162. 2023
• Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24(3). 2023
• Boldine Attenuates Synaptic Failure and Mitochondrial Deregulation in Cellular Models of Alzheimer's Disease.  FRONTIERS IN NEUROSCIENCE.  15. 2021
• Effects of the age/rage axis in the platelet activation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.  166:1149-1161. 2021
• Phenotypic characterization and predictive analysis of p.Asp47Asn LDL receptor mutation associated with Familial Hypercholesterolemia in a Chilean population.  JOURNAL OF CLINICAL LIPIDOLOGY.  15(2):366-374. 2021
• The stimulatory effects of intracellular a-synuclein on synaptic transmission are attenuated by 2-octahydroisoquinolin-2(1h)-ylethanamine.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22(24). 2021
• Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease.  NEUROBIOLOGY OF DISEASE.  141. 2020
• Contrasting responses of cluster roots formation induced by phosphorus and nitrogen supply in Embothrium coccineumpopulations from different geographical origin.  PLANT AND SOIL.  453(1-2):473-485. 2020
• Gabapentin Inhibits Multiple Steps in the Amyloid Beta Toxicity Cascade.  ACS CHEMICAL NEUROSCIENCE.  11(19):3064-3076. 2020
• Inhibition of the Glycine Receptor alpha 3 Function by Colchicine.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Modulation of glycine receptor single-channel conductance by intracellular phosphorylation.  SCIENTIFIC REPORTS.  10(1). 2020
• Anti-aggregation effect on platelets of Indiplon a hypnotic sedative non-benzodiazepine drug.  BIOMEDICINE & PHARMACOTHERAPY.  111:378-385. 2019
• Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function.  FRONTIERS IN PHARMACOLOGY.  10. 2019
• Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors.  ACS CHEMICAL NEUROSCIENCE.  10(5):2551-2559. 2019
• The cAMP/PKA Pathway Inhibits Beta-amyloid Peptide Release from Human Platelets.  NEUROSCIENCE.  397:159-171. 2019
• Neuroprotective effect of a new variant of Epo nonhematopoietic against oxidative stress.  REDOX BIOLOGY.  14:285-294. 2018
• Functional modulation of glycine receptors by the alkaloid gelsemine.  BRITISH JOURNAL OF PHARMACOLOGY.  173(14):2263-2277. 2016
• Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.  MOLECULAR PHARMACOLOGY.  90(3):318-325. 2016
• Control of Ethanol sensitivity of the Glycene receptor a3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain.  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  353:80-90. 2015
• Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses.  PHARMACOLOGICAL RESEARCH.  101:18-29. 2015
• Evidence for a-helices in the large intracellular domain mediating modulation of the alpha 1 glycine receptor by ethanol and GBy.  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  352(1):148-155. 2015
• Low concentrations of ethanol protect against synaptotoxicity induced by AB in hippocampal neurons.  NEUROBIOLOGY OF AGING.  36(2):845-856. 2015