artículo académico

• An Open-source Protocol for Deep Learning-based Segmentation of Tubular Structures in 3D Fluorescence Microscopy Images.  JOVE-JOURNAL OF VISUALIZED EXPERIMENTS.  225. 2025
• Endogenous Galectin-8 protects against Th17 infiltration and fibrosis following acute kidney injury.  MOLECULAR MEDICINE.  31(1). 2025
• Maternal regulation of the vertebrate oocyte-to-embryo transition.  PLOS GENETICS.  20(7). 2024
• Phenotypic characterization of liver tissue heterogeneity through a next-generation 3D single-cell atlas.  SCIENTIFIC REPORTS.  14(1). 2024
• Targeting the immunoproteasome in hypothalamic neurons as a novel therapeutic strategy for high-fat diet-induced obesity and metabolic dysregulation.  JOURNAL OF NEUROINFLAMMATION.  21(1). 2024
• Virtual tissue microstructure reconstruction across species using generative deep learning.  PLOS ONE.  19(7). 2024
• Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG.  BMC BIOLOGY.  18(1). 2020
• Quantification of nematic cell polarity in three-dimensional tissues.  PLOS COMPUTATIONAL BIOLOGY.  16(12). 2020
• Liquid-crystal organization of liver tissue.  ELIFE.  8. 2019
• Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.  NATURE MEDICINE.  21(12):1885-1893. 2019
• Content-aware image restoration: pushing the limits of fluorescence microscopy.  NATURE METHODS.  15(12):1090-1097. 2018
• Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse.  CELL REPORTS.  25(11):3110-3122. 2018
• A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule.  CELL SYSTEMS.  4(3):277-290. 2017
• Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.  PLOS ONE.  12(6). 2017
• A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture.  ELIFE.  4. 2015
• Anti-Ribosomal P Protein Autoantibodies From Patients With Neuropsychiatric Lupus Impair Memory in Mice.  ARTHRITIS & RHEUMATOLOGY.  67(1):204-214. 2015
• Pathogenicity of Lupus Anti-Ribosomal P Antibodies: Role of Cross-Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model.  ARTHRITIS & RHEUMATOLOGY.  67(6):1598-1610. 2015
• Increased concentration of plasminogen activator inhibitor-1 and fibrinogen in individuals with metabolic syndrome.  MOLECULAR MEDICINE REPORTS.  2(2):253-257. 2009
• Increased concentrations of soluble vascular cell adhesion molecule-1 and soluble CD40L in subjects with metabolic syndrome.  MOLECULAR MEDICINE REPORTS.  2(3):481-485. 2009
• Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development.  DEVELOPMENTAL BIOLOGY.  329(2):338-349. 2009
• Heme iron uptake by Caco-2 cells is a saturable, temperature sensitive and modulated by extracellular pH and potassium.  BIOLOGICAL TRACE ELEMENT RESEARCH.  125(2):109-119. 2008