artículo académico

• Vesicular Glutamate Release Is Necessary for Neural Tube Formation.  JOURNAL OF NEUROSCIENCE.  46(11). 2026
• Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide..  SCIENTIFIC REPORTS.  15(1). 2025
• The Alkaloid Gelsemine Reduces Aß Peptide Toxicity by Targeting Transglutaminase Type 2 Enzyme.  PLANTS-BASEL.  14(10). 2025
• Incidence of gestational diabetes in Chile during the period 2001-2022.  REVISTA CHILENA DE OBSTETRICIA Y GINECOLOGIA.  89(2):100-108. 2024
• Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  25(6). 2024
• COVID-19 on Pregnancy Outcomes, Mental Health and Placenta: Focus in Latin America.  ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.  1428:269-285. 2023
• Metabolic imprint induced by seed halo-priming promotes a differential physiological performance in two contrasting quinoa ecotypes.  FRONTIERS IN PLANT SCIENCE.  13. 2023
• Modulation of GABAA receptors and of GABAergic synapses by the natural alkaloid gelsemine.  FRONTIERS IN MOLECULAR NEUROSCIENCE.  15. 2023
• Nitrogen sources differentially affect respiration, growth, and carbon allocation in Andean and Lowland ecotypes of Chenopodium quinoa Willd.  FRONTIERS IN PLANT SCIENCE.  14. 2023
• TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer's disease.  BIOMEDICINE & PHARMACOTHERAPY.  162. 2023
• Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24(3). 2023
• Antiseizure medication in early nervous system development. Ion channels and synaptic proteins as principal targets.  FRONTIERS IN PHARMACOLOGY.  13. 2022
• Increased P2x2 receptors induced by amyloid-beta peptide participates in the neurotoxicity in alzheimer's disease.  BIOMEDICINE & PHARMACOTHERAPY.  142. 2021
• The Omega-3 fatty acid docosahexaenoic acid selectively induces apoptosis in tumor-derived cells and suppress tumor growth in gastric cancer.  EUROPEAN JOURNAL OF PHARMACOLOGY.  896. 2021
• Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Inhibition of the Glycine Receptor alpha 3 Function by Colchicine.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Modulation of glycine receptor single-channel conductance by intracellular phosphorylation.  SCIENTIFIC REPORTS.  10(1). 2020
• Seed characterization and early nitrogen metabolism performance of seedlings from Altiplano and coastal ecotypes of Quinoa.  BMC PLANT BIOLOGY.  20(1). 2020
• Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers.  JOURNAL OF CHEMICAL INFORMATION AND MODELING.  60(12):6634-6641. 2020
• 17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-beta Toxicity by Nicotinic Acetylcholine Receptors.  JOURNAL OF ALZHEIMERS DISEASE.  67(1):343-356. 2019
• Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors.  FRONTIERS IN PHARMACOLOGY.  10:1-15. 2019
• Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function.  FRONTIERS IN PHARMACOLOGY.  10. 2019
• Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors.  ACS CHEMICAL NEUROSCIENCE.  10(5):2551-2559. 2019
• NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects.  JOURNAL OF NEUROSCIENCE.  38(20):4762-4773. 2018
• Opposing roles of calcium and intracellular ATP on gating of the purinergic P2X2 receptor channel.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  19(4):1-19. 2018
• Altered sedative effects of ethanol in mice with a1 glycine receptor subunits that are insensitive to GBy modulation .  NEUROPSYCHOPHARMACOLOGY.  39(11):2538-2548. 2014