artículo académico

• Production of Novel Thermostable Esterases from Thermus thermophilus Strain ET-1 in Escherichia coli and Thermus thermophilus HB27 Using the Bifunctional Expression System pTGT-1 and Characterization of the Recombinant Enzymes.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  27(3). 2026
• Evaluation of antioxidant activity and polyphenol preservation in rosehip (Rosa spp.) during storage and convective drying.  LWT-FOOD SCIENCE AND TECHNOLOGY.  228. 2025
• Structural and Functional Characterization of LIMCH1 and Its Agmatinase-like Region: A Case of Catalysis in a Highly Disordered Protein.  BIOMOLECULES.  15(11). 2025
• Biodegradation of Polystyrene by Galleria mellonella: Identification of Potential Enzymes Involved in the Degradative Pathway.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  25(3). 2024
• Enhancing late postmortem interval prediction: a pilot study integrating proteomics and machine learning to distinguish human bone remains over 15 years.  BIOLOGICAL RESEARCH.  57(1). 2024
• In Silico Analysis of the Molecular Interaction between Anthocyanase, Peroxidase and Polyphenol Oxidase with Anthocyanins Found in Cranberries.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  25(19). 2024
• A new approach to the induction and recovery of Synechococcus leopoliensis CPD-photolyase for cosmetic applications.  JOURNAL OF APPLIED PHYCOLOGY.  34(5):2371-2382. 2022
• A rationale for the unlike potency of avibactam and ETX2514 against OXA-24 ß-lactamase.  ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS.  727. 2022
• GKRP-dependent modulation of feeding behavior by tanycyte-released monocarboxylates.  THERANOSTICS.  12(4):1518-1536. 2022
• New Insights into the Determinants of Specificity in Human Type I Arginase: Generation of a Mutant That Is Only Active with Agmatine as Substrate.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  23(12). 2022
• A theoretical approach for the acylation/deacylation mechanisms of avibactam in the reversible inhibition of KPC-2.  JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN.  35(9):943-952. 2021
• Crystal Structure of Escherichia coli Agmatinase: Catalytic Mechanism and Residues Relevant for Substrate Specificity.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22(9). 2021
• Biosynthesis and characterization of a recombinant eukaryotic allophycocyanin using prokaryotic accessory enzymes.  MICROBIOLOGYOPEN.  9(3). 2020
• Insights into the Mn2+ Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  21(11). 2020
• Insights on the participation of Glu256 and Asp204 in the oligomeric structure and cooperative effects of human arginase type I.  JOURNAL OF STRUCTURAL BIOLOGY.  211(2). 2020
• The FGF2-induced tanycyte proliferation involves a connexin 43 hemichannel/purinergic-dependent pathway.  JOURNAL OF NEUROCHEMISTRY.  156(2):182-199. 2020
• Tympanic Membrane Rupture During Stereotaxic Surgery Disturbs the Normal Feeding Behavior in Rats.  FRONTIERS IN BEHAVIORAL NEUROSCIENCE.  14. 2020
• When a Little Bit More Makes the Difference: Expression Levels of GKRP Determines the Subcellular Localization of GK in Tanycytes.  FRONTIERS IN NEUROSCIENCE.  13:1-14. 2019
• Glial hypothalamic inhibition of GLUT2 expression alters satiety, impacting eating behavior.  GLIA.  66(3):592-605. 2018
• Plasmatic Concentrations of ADMA and Homocystein in Llama (Lama glama) and Regulation of Arginase Type II: An Animal Resistent to the Development of Pulmonary Hypertension Induced by Hypoxia.  FRONTIERS IN PHYSIOLOGY.  9:1-10. 2018
• Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior.  SCIENTIFIC REPORTS.  7:1-13. 2017
• Mammalian agmatinases constitute unusual members in the family of Mn2+-dependent ureahydrolases.  JOURNAL OF INORGANIC BIOCHEMISTRY.  166:122-125. 2017
• Molecular and functional characterization of ferredoxin NADP(H) oxidoreductase from Gracilaria chilensis and its complex with ferredoxin.  BIOLOGICAL RESEARCH.  50:1-10. 2017
• Cloning of two LIMCH1 isoforms: characterization of their distribution in rat brain and their agmatinase activity.  HISTOCHEMISTRY AND CELL BIOLOGY.  145:305-313. 2016
• Insight on the interaction of an agmatinase-like protein with Mn (2+) activator ions.  JOURNAL OF INORGANIC BIOCHEMISTRY.  145:65-69. 2015
• Mutagenic and kinetic support for an allosteric site in arginase from the extreme thermophile Bacillus caldovelox, which allows activation by arginine.  BIOCHIMIE.  108:8-12. 2015
• Dynamic Localization of Glucokinase adn regulatory Protein Hypothalamic Tanycytes.  PLOS ONE.  9(4):1-18. 2014
• Further insight into the inhibitory action of a LIM/double zinc-finger motif of an agmatinase-like protein.  JOURNAL OF INORGANIC BIOCHEMISTRY.  132:92-95. 2014
• Evidence for an Inhibitory LIM Domain in a Rat Brain Agmatinase-Like Protein.  ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS.  512:107-110. 2011
• Xenobiotic-induced changes in the arginase activity of zebrafisch (Danio Rerio) Eleutheroembryo.  ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY.  30(10):2285-2291. 2011
• Expression and Localization of an Agmatinase-Like Protein in the Rat Brain.  HISTOCHEMISTRY AND CELL BIOLOGY.  134:137-144. 2010
• Cloning and Functional Expression of a Rodent Brain cDNA Encoding a Novel Protein with Agmatinase Activity, but not Belonging to the Arginase Family.  ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS.  461:146-150. 2007
• Low Temperature Regulates Sucrose-Phosphate Synthase Activity in Colobanthus quitensis (Kunth) Bartl. by Decreasing its Sensitivity to Pi and Increased Activation by Glucose-6-Phosphate.  POLAR BIOLOGY.  29:1011-1017. 2006
• Mutational Analysis of Substrate Recognition by Human Arginase Type I-Agmatinase Activity of the N130D Variant.  FEBS JOURNAL.  273:5625-5631. 2006
• Insights Into the Interaction of Human Arginase II With Substrate and Manganese Ions by Site-Directed Mutagenesis and Kinetic Studies. Alteration of Substrate Specificity by Replacement of Asn149 With Asp.  FEBS JOURNAL.  272(17):4540-4548. 2005
• Inactivation of Human Liver Arginase by Woodward's Reagent K: Evidence for Reaction with His141.  PROTEIN JOURNAL.  23(3):179-183. 2004
• Kinetic Studies and Site-Directed Mutagenesis of Escherichia coli Agmatinase. A Role for Glu274 in Binding and Correct Positioning of the Substrate Guanidinium Group.  ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS.  430:185-190. 2004
• Non-Chelating Inhibition of the H101N Variant of Human Liver Arginase by EDTA.  JOURNAL OF INORGANIC BIOCHEMISTRY.  98:1465-1469. 2004
• Studies on the Interaction of Escherichia coli Agmatinase with Manganese Ions: Structural and Kinetic Studies of the H126N and H151N Variants.  JOURNAL OF INORGANIC BIOCHEMISTRY.  98:1032-1035. 2004