artículo académico

• Design and functional characterization of Salmo salar TLR5 agonist peptides derived from high mobility group B1 acidic tail.  FISH & SHELLFISH IMMUNOLOGY.  146. 2024
• New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides.  FRONTIERS IN IMMUNOLOGY.  15. 2024
• Chitosan Microparticles Enhance the Intestinal Release and Immune Response of an Immune Stimulant Peptide in Oncorhynchus mykiss.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24(19). 2023
• Co-Formulation of Recombinant Porcine IL-18 Enhances the Onset of Immune Response in a New Lawsonia intracellularis Vaccine.  VACCINES.  11(12). 2023
• Design and Construction of a Synthetic Nanobody Library: Testing Its Potential with a Single Selection Round Strategy.  MOLECULES.  28(9). 2023
• Effects of recombinant FSH (bscrFSH) and pituitary FSH (FSH-p) on embryo production in superovulated dairy heifers inseminated with unsorted and sex-sorted semen.  ANIMAL REPRODUCTION SCIENCE.  252. 2023
• First report of bovine viral diarrhea virus subgenotypes 1d and 1e in southern Chile.  VIROLOGY JOURNAL.  20(1). 2023
• Immunomodulatory role of vasoactive intestinal peptide and ghrelin in Oncorhynchus mykiss.  HELIYON.  9(12). 2023
• New Formulation of a Subunit Vaccine Candidate against Lawsonia intracellularis Increases Humoral and Cellular Immune Responses.  VACCINES.  11(12). 2023
• Selecting Nanobodies Specific for the Epidermal Growth Factor from a Synthetic Nanobody Library.  MOLECULES.  28(10). 2023
• EFFECTS OF EXTRA-LONG-ACTING RECOMBINANT BOVINE FSH (BSCRFSH) ON CATTLE SUPEROVULATION.  ANIMALS.  12(2). 2022
• Long-term release of bioactive interferon-alpha from plga-chitosan microparticles: in vitro and in vivo studies.  BIOMATERIALS ADVANCES.  143. 2022
• STRUCTURE-BASED DESIGN AND CONSTRUCTION OF A SYNTHETIC PHAGE DISPLAY NANOBODY LIBRARY.  BMC RESEARCH NOTES.  15(1). 2022
• A TRIVALENT TNF-R2 AS A NEW TUMOR NECROSIS FACTOR ALPHA-BLOCKING MOLECULE.  PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS.  89(11):1557-1564. 2021
• CHARACTERISATION OF A NEW MOLECULE BASED ON TWO E2 SEQUENCES FROM BOVINE VIRAL DIARRHOEA-MUCOSAL DISEASE VIRUS FUSED TO THE HUMAN IMMUNOGLOBULIN FC FRAGMENT.  JOURNAL OF VETERINARY RESEARCH.  65(1):27-37. 2021
• DESIGN AND CHARACTERIZATION OF A NOVEL DIMERIC BLOOD-BRAIN BARRIER PENETRATING TNF ALPHA INHIBITOR.  PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS.  89(11):1508-1521. 2021
• EXPRESSION AND CHARACTERIZATION OF A NOVEL SINGLE-CHAIN ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR ANTIBODY IN THE GOAT MILK.  JOURNAL OF BIOTECHNOLOGY.  338:52-62. 2021
• IN VIVO MODIFICATION OF THE GOAT MAMMARY GLAND GLYCOSYLATION PATHWAY.  NEW BIOTECHNOLOGY.  61:11-21. 2021
• A HETEROLOGOUS VIRAL PROTEIN SCAFFOLD FOR CHIMERIC ANTIGEN DESIGN: AN EXAMPLE PCV2 VIRUS VACCINE CANDIDATE.  VIRUSES-BASEL.  12(4). 2020
• FLUORESCENCE-ASSISTED SEQUENTIAL INSERTION OF TRANSGENES (FASIT): AN APPROACH FOR INCREASING SPECIFIC PRODUCTIVITY IN MAMMALIAN CELLS.  SCIENTIFIC REPORTS.  10(1):1-6. 2020
• NEW INSIGHTS ON THE INTERACTION MECHANISM OF RHTNFA WITH ITS ANTAGONISTS ADALIMUMAB AND ETANERCEPT.  BIOCHEMICAL JOURNAL.  477(17):3299-3311. 2020
• AAV PURIFICATION BY ANION-EXCHANGE CHROMATOGRAPHY.  REVISTA BIONATURA.  4(1):771-774. 2019
• EXPRESSION AND CHARACTERIZATION OF HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCED IN SIHA CELLS TRANSDUCED WITH ADENOVIRAL VECTOR.  PROTEIN JOURNAL.  38(6):693-703. 2019
• FISH & SHELLFISH IMMUNOLOGY.  FISH & SHELLFISH IMMUNOLOGY.  88:587-594. 2019
• MULTI-ANTIGENIC RECOMBINANT SUBUNIT VACCINE AGAINST LAWSONIA INTRACELLULARIS: THE ETIOLOGICAL AGENT OF PORCINE PROLIFERATIVE ENTEROPATHY.  VACCINE.  37(10):1340-1349. 2019
• ACTIVATION OF MEMBRANE-BOUND AND SOLUBLE TOLL-LIKE RECEPTORS 5 IN SALMO SALAR DEPENDS ON THE MYD88 SIGNALLING PATHWAY.  BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS.  1862(10):2215-2225. 2018
• LOX-1 ACTIVATION BY OXLDL TRIGGERS AN EPITHELIAL MESENCHYMAL TRANSITION AND PROMOTES TUMORIGENIC POTENTIAL IN PROSTATE CANCER CELLS.  CANCER LETTERS.  414:34-43. 2018
• NEUROPROTECTIVE EFFECT OF A NEW VARIANT OF EPO NONHEMATOPOIETIC AGAINST OXIDATIVE STRESS.  REDOX BIOLOGY.  14:285-294. 2018
• QUANTITATIVE ELISA SANDWICH FOR A NEW VACCINE AGAINST AVIAN INFLUENZA VIRUS H5N1.  JOURNAL OF IMMUNOLOGICAL METHODS.  459:70-75. 2018
• EDUCACION MEDICA SUPERIOR.  EDUCACION MEDICA SUPERIOR.  31(1):78-88. 2017
• EXPRESSION AND PURIFICATION OF THE SURFACE PROTEINS FROM ANDES VIRUS.  PROTEIN EXPRESSION AND PURIFICATION.  139:63-70. 2017
• ATOMIC STRUCTURE AND BIOCHEMICAL CHARACTERIZATION OF AN RNA ENDONUCLEASE IN THE N TERMINUS OF ANDES VIRUS L PROTEIN.  PLOS PATHOGENS.  12(6):1-18. 2016
• BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS.  BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS.  1850(9):1685-1693. 2015
• CIS-REGULATORY ELEMENTS INVOLVED IN SPECIES-SPECIFIC TRANSCRIPTIONAL REGULATION OF THE SVCT1 GENE IN RAT AND HUMAN HEPATOMA CELLS.  FREE RADICAL BIOLOGY AND MEDICINE.  85:183-196. 2015
• SECRETION AND ASSEMBLY OF CALICIVIRUS-LIKE PARTICLES IN HIGH-CELL-DENSITY YEAST FERMENTATIONS:STRATEGIES BASED ON A RECOMBINANT NON-SPECIFIC BPTI-KUNITZ-TYPE PROTEASE INHIBITOR.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY.  99:3875-3886. 2015
• EFFECTIVENESS OF THE E2-CLASSICAL SWINE FEVER VIRUS RECOMBINANT VACCINE PRODUCED AND FORMULATED WITHIN THE WHEY OF GENETICALLY TRANSFORMED GOATS.  CLINICAL AND VACCINE IMMUNOLOGY.  21(12):1628-1634. 2014
• LECTIN-LIKE OXIDIZED LDL RECEPTOR-1 IS AN ENHANCER OF TUMOR ANGIOGENESIS IN HUMAN PROSTATE CANCER CELLS.  PLOS ONE.  9(8):1-11. 2014
• FIRST REPORT OF BOVINE HERPESVIRUS 5 IN BULL SEMEN.  ARCHIVES OF VIROLOGY.  157(9):1775-1778. 2012
• AVIAN CD154 ENHANCES HUMORAL AND CELLULAR IMMUNE RESPONSES INDUCED BY AN ADENOVIRUS VECTOR-BASED VACCINE IN CHICKENSHE.  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES.  0. 2011
• DUAL PROMOTER LENTIVIRAL VECTOR GENERATES TRANSGENIC MICE EXPRESSING E2-CSFV GLYCOPROTEIN IN THEIR MILK, BUT IMPAIRS EARLY IDENTIFICATION OF THE TRANSGENIC EMBRYOS.  THERIOGENOLOGY.  0. 2011
• ALL ROADS LEAD TO MILK: TRANSGENIC AND NON-TRANSGENIC APPROACHES FOR EXPRESSION OF RECOMBINANT PROTEINS IN THE MAMMARY GLAND.  ACTA SCIENTIAE VETERINARIAE.  38(2):615-627. 2010
• EARLY ONSET AND LONG LASTING PROTECTION IN PIGS PROVIDED BY A CLASSICAL SWINE FEVER E2-VACCINE CANDIDATE PRODUCED IN THE MILK OF GOATS.  VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY.  133(1):25-32. 2010
• HUMAN ALFAIFN CO-FORMULATED WITH MILK DERIVED E2-CSFV PROTEIN INDUCE EARLY FULL PROTECTION IN VACCINATED PIGS.  VACCINE.  0. 2010