artículo académico

• Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  25(6). 2024
• BIOMEDICINE & PHARMACOTHERAPY.  BIOMEDICINE & PHARMACOTHERAPY.  162. 2023
• MODULATION OF GABAA RECEPTORS AND OF GABAERGIC SYNAPSES BY THE NATURAL ALKALOID GELSEMINE.  FRONTIERS IN MOLECULAR NEUROSCIENCE.  15. 2023
• PARTIAL INHIBITION OF COMPLEX I RESTORES MITOCHONDRIAL MORPHOLOGY AND MITOCHONDRIA-ER COMMUNICATION IN HIPPOCAMPUS OF APP/PS1 MICE.  CELLS.  12(8). 2023
• UNDERSTANDING THE ROLE OF ATP RELEASE THROUGH CONNEXINS HEMICHANNELS DURING NEURULATION.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  24(3). 2023
• ANTISEIZURE MEDICATION IN EARLY NERVOUS SYSTEM DEVELOPMENT. ION CHANNELS AND SYNAPTIC PROTEINS AS PRINCIPAL TARGETS.  FRONTIERS IN PHARMACOLOGY.  13. 2022
• METABOLIC PROFILE AND ANTIOXIDANT CAPACITY OF FIVE BERBERIS LEAVES SPECIES: A COMPREHENSIVE STUDY TO DETERMINE THEIR POTENTIAL AS NATURAL FOOD OR INGREDIENT.  FOOD RESEARCH INTERNATIONAL.  160. 2022
• BIOMEDICINE & PHARMACOTHERAPY.  BIOMEDICINE & PHARMACOTHERAPY.  142. 2021
• PHENOLIC COMPOUNDS IN CALAFATE BERRIES ENCAPSULATED BY SPRAY DRYING: NEUROPROTECTION POTENTIAL INTO THE INGREDIENT.  ANTIOXIDANTS.  10(11). 2021
• THE ADMINISTRATION OF THE SYNBIOTIC LACTOBACILLUS BULGARICUS 6C3 STRAIN, INULIN AND FRUCTOOLIGOSACCHARIDE DECREASES THE CONCENTRATIONS OF INDOXYL SULFATE AND KIDNEY DAMAGE IN A RAT MODEL.  TOXINS.  13(3). 2021
• ALTERED GLUTAMINASE 1 ACTIVITY DURING NEURULATION AND ITS POTENTIAL IMPLICATIONS IN NEURAL TUBE DEFECTS.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• CHANGES IN PGC-1 ALPHA/SIRT1 SIGNALING IMPACT ON MITOCHONDRIAL HOMEOSTASIS IN AMYLOID-BETA PEPTIDE TOXICITY MODEL.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• FRONTIERS IN PHARMACOLOGY.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• MODULATION OF GLYCINE RECEPTOR SINGLE-CHANNEL CONDUCTANCE BY INTRACELLULAR PHOSPHORYLATION.  SCIENTIFIC REPORTS.  10(1). 2020
• STEREOSPECIFIC INHIBITION OF ETHANOL POTENTIATION ON GLYCINE RECEPTOR BY M554 STEREOISOMERS.  JOURNAL OF CHEMICAL INFORMATION AND MODELING.  60(12):6634-6641. 2020
• 17 OXO SPARTEINE AND LUPANINE, OBTAINED FROM CYTISUS SCOPARIUS, EXERT A NEUROPROTECTION AGAINST SOLUBLE OLIGOMERS OF AMYLOID-BETA TOXICITY BY NICOTINIC ACETYLCHOLINE RECEPTORS.  JOURNAL OF ALZHEIMERS DISEASE.  67(1):343-356. 2019
• EXPLORING THE ROLE OF P2X RECEPTORS IN ALZHEIMER'S DISEASE.  FRONTIERS IN PHARMACOLOGY.  10:1330-1339. 2019
• EXPOSURE TO UV-B RADIATION LEADS TO INCREASED DEPOSITION OF CELL WALL-ASSOCIATED XEROCOMIC ACID IN CULTURES OF SERPULA HIMANTIOIDES.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY.  85(18):1-13. 2019
• INHIBITORY ACTIONS OF TROPEINES ON THE ALPHA 3 GLYCINE RECEPTOR FUNCTION.  FRONTIERS IN PHARMACOLOGY.  10. 2019
• LARGE INTRACELLULAR DOMAIN-DEPENDENT EFFECTS OF POSITIVE ALLOSTERIC MODULATORS ON GLYCINE RECEPTORS.  ACS CHEMICAL NEUROSCIENCE.  10(5):2551-2559. 2019
• NEUROPROTECTIVE EFFECTS OF EPOL AGAINST OXIDATIVE STRESS INDUCED BY SOLUBLE OLIGOMERS OF A BETA PEPTIDE.  INTERNATIONAL JOURNAL FOR PARASITOLOGY-PARASITES AND WILDLIFE.  24:1-12. 2019
• A NATURAL BENZOFURAN FROM THE PATAGONIC ALEURODISCUS VITELLINUS FUNGUS HAS POTENT NEUROPROTECTIVE PROPERTIES ON A CELLULAR MODEL OF AMYLOID-BETA PEPTIDE TOXICITY.  JOURNAL OF ALZHEIMERS DISEASE.  61(4):1463-1475. 2018
• CYTOTOXICITY AND IN VIVO PLASMA KINETIC BEHAVIOR OF SURFACE-FUNCTIONALIZED PAMAM DENDRIMERS.  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE.  14(7):2227-2234. 2018
• NANOMATERIALS.  NANOMATERIALS.  8(1):1-12. 2018
• NEUROPHARMACOLOGY.  NEUROPHARMACOLOGY.  128:366-378. 2018
• NEUROPROTECTIVE EFFECT OF A NEW VARIANT OF EPO NONHEMATOPOIETIC AGAINST OXIDATIVE STRESS.  REDOX BIOLOGY.  14:285-294. 2018
• ATP LEAKAGE INDUCES P2XR ACTIVATION AND CONTRIBUTES TO ACUTE SYNAPTIC EXCITOTOXICIW INDUCED BY SOLUBLE OLIGOMERS OF BETA-AMYLOID PEPTIDE IN HIPPOCAMPAL NEURONS.  NEUROPHARMACOLOGY.  100:116-123. 2016
• BIOEQUIVALENCE STUDY OF TWO HYDROCHLOROTHIAZIDE FORMULATIONS AFTER ORAL ADMINISTRATION IN HEALTHY CHILEAN VOLUNTEERS.  JOURNAL OF PHARMACY AND PHARMACOLOGY.  4:679-685. 2016
• FUNCTIONAL MODULATION OF GLYCINE RECEPTORS BY THE ALKALOID GELSEMINE.  BRITISH JOURNAL OF PHARMACOLOGY.  173(14):2263-2277. 2016
• IMPACT OF MITICHONDRIAL DYSFUNCTION ON NEURODEGENERATIVE DISEASES: A KEY STEP ON ALZHEIMER´S DISEASE 2016
• REVERSAL OF ETHANOL-INDUCED INTOXICATION BY A NOVEL MODULATOR OF Gß¿ POTENTIATION OF GLYCINE RECEPTOR.  JOURNAL OF BIOLOGICAL CHEMISTRY.  291:18791-18798. 2016
• HARMFUL ALGAE.  HARMFUL ALGAE.  47:1-8. 2015
• MODULATION OF THE NEURONAL NETWORK ACTIVITY BY P2X RECEPTORS AND THEIR INVOLVEMENT IN NEUROLOGICAL DISORDERS.  PHARMACOLOGICAL RESEARCH.  109-115. 2015
• COPPER-UPTAKE IS CRITICAL FOR THE DOWN REGULATION OF SYNAPSIN AND DYNAMIN INDUCED BY NEOCUPROINE: MODULATION OF SYNAPTIC ACTIVITY IN HIPPOCAMPAL NEURONS.  FRONTIERS IN AGING NEUROSCIENCE.  6(319):1-10. 2014
• MODULATION OF NEURONAL NICOTINIC RECEPTOR BY QUINOLIZIDINE ALKALOIDS CAUSES NEUROPROTECTION ON A CELLULAR ALZHEIMER MODEL.  JOURNAL OF ALZHEIMERS DISEASE.  42(1):143-155. 2014
• INHIBITION OF THE ETHANOL-INDUCED POTENTIATION OF A1 GLYCINE RECEPTOR BY A SMALL PEPTIDE THAT INTERFERES WITH GBY BINDING.  JOURNAL OF BIOLOGICAL CHEMISTRY.  287(48):40713-40721. 2012
• SYNAPTIC SILENCING AND PLASMA MEMBRANE DYSHOMEOSTASIS INDUCED BY AMYLOID-B PEPTIDE ARE PREVENTED BY ARISTOTELIA CHILENSIS ENRICHED EXTRACT.  JOURNAL OF ALZHEIMERS DISEASE.  31:879-889. 2012
• CHEMICAL & PHARMACEUTICAL BULLETIN.  CHEMICAL & PHARMACEUTICAL BULLETIN.  59(2):161-165. 2011
• CLONING AND SPATIOTEMPORAL EXPRESSION OF RIC-8 IN XENOPUS EMBRYOGENESIS.  GENE EXPRESSION PATTERNS.  11:401-408. 2011
• SYNAPTIC FAILURE AND ADENOSINE TRIPHOSPHATE IMBALANCE INDUCED BY AMYLOID-B AGGREGATES ARE PREVENTED BY BLUEBERRY-ENRICHED POLYPHENOL EXTRACT.  JOURNAL OF NEUROSCIENCE RESEARCH.  89:1499-1508. 2011
• IMPACT OF BALANCE TRAINING WITH A VIRTUAL REALITY IN ELDERLY.  INTERNATIONAL JOURNAL OF MORPHOLOGY.  28(1):303-308. 2010
• IMPACTO DEL ENTRENAMIENTO DEL BALANCE A TRAVÉS DE REALIDAD VIRTUAL EN UNA POBLACIÓN DE ADULTOS MAYORES.  INTERNATIONAL JOURNAL OF MORPHOLOGY.  28(1):303-308. 2010
• POTENTIATION AND INHIBITION OF GLYCINE RECEPTORS BY TUTIN.  NEUROPHARMACOLOGY.  2010
• BLOCKADE OF ETHANOL-INDUCED POTENTIATION OF GLYCINE RECEPTORS BY A PEPTIDE THAT INTERFERES WITH GBETASIGMA BINDING.  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  331(3):933-939. 2009
• EUROPEAN JOURNAL OF PHARMACOLOGY.  EUROPEAN JOURNAL OF PHARMACOLOGY.  559:61-64. 2007
• TIGHT COUPLING OF THE T-SNARE AND CALCIUM CHANNEL MICRODOMAINS IN ADRENOMEDULLARY SLICES AND NOT IN CULTURED CHRAMAFFIN CELLS.  CELL CALCIUM.  41:547-558. 2007
• HISTORICAL AND CURRENT PERSPECTIVES OF NEUROACTIVE COMPOUNDS DERIVED FROM LATIN AMERICA.  JOURNAL OF MEDICINAL CHEMISTRY.  6:997-1008. 2006