artículo académico

• Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021.  LANCET PUBLIC HEALTH.  10(3):172-188. 2025
• Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019.  NATURE COMMUNICATIONS.  16(1). 2025
• Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage. The Global Burden of Disease Study 2021.  JAMA NEUROLOGY.  82(8):765-787. 2025
• Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study.  NATURE MEDICINE.  31(6):1809-1829. 2025
• Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET INFECTIOUS DISEASES.  25(5):519-536. 2025
• Global, regional, and national burden of epilepsy, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET PUBLIC HEALTH.  10(3):203-227. 2025
• Global, regional, and national burden of pulmonary arterial hypertension, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET RESPIRATORY MEDICINE.  13(1):69-79. 2025
• Global, regional, and national prevalence of adult overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.  LANCET.  405(10481):813-838. 2025
• Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.  LANCET.  405(10481):785-812. 2025
• Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023.  LANCET.  406(10500):235-260. 2025
• Healthy Eating Score and All-Cause Mortality: Prospective Findings from the Chilean National Health Survey.  BRITISH JOURNAL OF NUTRITION.  1-25. 2025
• Physical inactivity and risk of all-cause mortality in Chile: Results of the 2009-2010 National Health Survey.  REVISTA MEDICA DE CHILE.  153(6):401-413. 2025
• Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest.  CRITICAL REVIEWS IN BIOTECHNOLOGY.  44(2):319-336. 2024
• Association between a lifestyle score and all-cause mortality: A prospective analysis of the Chilean National Health Survey 2009-2010.  PUBLIC HEALTH NUTRITION.  27(1). 2024
• Association between the rs12654778 SNP of the ß-2 adrenergic receptor and LDL cholesterol levels in the Chilean adult population.  ENDOCRINOLOGIA DIABETES Y NUTRICION.  71(9):397-404. 2024
• Associations between diabesity and allcause mortality: a prospective analysis of the Chilean National Health Survey 2009-2010.  SALUD PUBLICA DE MEXICO.  66(6):798-806. 2024
• Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021.  LANCET.  403(10440):2204-2256. 2024
• Cocoa as immunomodulatory agent: an update.  NATURAL PRODUCT RESEARCH.  38(23):4196-4207. 2024
• Correlation between CUN-BAE, Body Mass Index, and Waist Circumference in Chilean Adults: Analysis of data from the 2016-17 Chilean National Health Survey.  REVISTA ESPANOLA DE NUTRICION HUMANA Y DIETETICA.  28(2):124-134. 2024
• Effectiveness of Resistance Training Program on Body Composition in Adults Following Vegan Diet versus Omnivorous Diet; Developed in Mobile Health Modality.  NUTRIENTS.  16(15). 2024
• Effects of video-guided active breaks with curricular content on mental health and classroom climate in chilean schoolchildren aged 6 to 10: study protocol for a multicentre randomized controlled trial.  FRONTIERS IN PHYSIOLOGY.  15. 2024
• Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET PUBLIC HEALTH.  9(10):e729-e744. 2024
• Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.  LANCET.  403(10440):1989-2956. 2024
• Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET.  403(10440):2162-2203. 2024
• Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET.  403(10440):2100-2132. 2024
• Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050.  LANCET.  404(10459):1199-1226. 2024
• Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.  LANCET.  403(10440):2057-2099. 2024
• Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET.  403(10440):2133-2161. 2024
• Global, regional, and national burden of HIV/AIDS, 1990-2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021.  LANCET HIV.  11(12):807-822. 2024
• Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET NEUROLOGY.  23(4):344-381. 2024
• Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET NEUROLOGY.  23(10):973-1003. 2024
• Global, regional, and national progress towards the 2030 global nutrition targets and forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET.  404(20471):2543-2583. 2024
• Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990-2021: findings from the Global Burden of Disease Study 2021.  LANCET.  404(10466):1955-1988. 2024
• Phytotoxicity Evaluation of Five Proton-Pump Inhibitors Through Plant-Based Eukaryotic Test Models.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION B-BIOLOGICAL SCIENCES.  94(1):93-100. 2024
• Prevalence of prediabesity and diabesity. Analysis of data from the 2016-17 Chilean National Health Survey.  REVISTA MEDICA DE CHILE.  152(2):178-186. 2024
• ABSI obesity index and its association with type 2 diabetes mellitus in Chilean adults: a cross-sectional study of the ENS 2016-2017.  REVISTA MEDICA DE CHILE.  151(6):687-695. 2023
• Body Adiposity Partially Mediates the Association between FTO rs9939609 and Lower Adiponectin Levels in Chilean Children.  CHILDREN-BASEL.  10(3). 2023
• Burden of disease due to amphetamines, cannabis, cocaine, and opioid use disorders in South America, 1990-2019: a systematic analysis of the Global Burden of Disease Study 2019.  LANCET PSYCHIATRY.  10(2):85-97. 2023
• Comparison of Diagnostic Models to Estimate the Risk of Metabolic Syndrome in a Chilean Pediatric Population: A Cross-Sectional Study.  METABOLITES.  13(2). 2023
• Effect of Sedentary behaviors on the Interaction Between the FTO Gene and Adiposity Levels in Chilean Adults - Results from the GENADIO Study.  REVISTA MEDICA DE CHILE.  151(8):980-991. 2023
• Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026.  LANCET GLOBAL HEALTH.  11(3):385-413. 2023
• Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021.  LANCET.  402(10397):203-234. 2023
• Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.  LANCET NEUROLOGY.  22(8):685-711. 2023
• Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019.  ECLINICALMEDICINE.  64. 2023
• Metabolic and cardiorespiratory fitness changes in women undergoing a physical exercise program assisted by a mobile application. A non-randomized controlled study.  REVISTA MEDICA DE CHILE.  151(7):869-879. 2023
• Motivation, barriers and benefits for the practice of physical exercise in a mobile health intervention in adults from Biobío, Chile.  RETOS-NUEVAS TENDENCIAS EN EDUCACION FISICA DEPORTE Y RECREACION.  49:623-631. 2023
• Myristicin: From its biological effects in traditional medicine in plants to preclinical studies and use as ecological remedy in plant protection.  EFOOD.  483). 2023
• Oxidative stress mediated cytogenotoxicological effects of phytol in wistar albino rats.  ADVANCES IN TRADITIONAL MEDICINE.  23(1):273-290. 2023
• Plant-food-derived Bioactives in Managing Hypertension: From Current Findings to Upcoming Effective Pharmacotherapies.  CURRENT TOPICS IN MEDICINAL CHEMISTRY.  23(8):589-617. 2023
• The burden of antimicrobial resistance in the Americas in 2019: a cross-country systematic analysis.  LANCET REGIONAL HEALTH-AMERICAS.  25. 2023
• The global fatty liver disease Sustainable Development Goal country score for 195 countries and territories.  HEPATOLOGY.  78(3):911-928. 2023
• Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles.  OXIDATIVE MEDICINE AND CELLULAR LONGEVITY.  2022. 2022
• Association between educational level and suspicion of cognitive imparirment in Chilean older people.  REVISTA MEDICA DE CHILE.  150(11):1575-1584. 2022
• Dietary Guidelines compliance among older chilean adults: A descriptive study of the 2016-2017 National Health Survey.  REVISTA CHILENA DE NUTRICION.  49(1):70-78. 2022
• Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019.  LANCET.  400(10369):2221-2248. 2022
• Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.  LANCET GASTROENTEROLOGY & HEPATOLOGY.  7(7):627-647. 2022
• In Silico Screening of Natural Products as Potential Inhibitors of SARS-CoV-2 Using Molecular Docking Simulation.  CHINESE JOURNAL OF INTEGRATIVE MEDICINE.  28(3):249-256. 2022
• Lifestyle modifications of chilean adolescents during the first COVID-19 confinement.  REVISTA MEDICA DE CHILE.  150(4):483-492. 2022
• Natural Compounds or Their Derivatives against Breast Cancer: A Computational Study.  BIOMED RESEARCH INTERNATIONAL.  2022. 2022
• Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.  233. 2022
• Physical Fitness, Screen Time and Sleep Habits According to Obesity Levels in Schoolchildren: Findings from the Health Survey of the Extreme South of Chile.  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH.  19(20). 2022
• Risk Factors and Gender Differences for Depression in Chilean Older Adults: A Cross-Sectional Analysis from the National Health Survey 2016-2017.  INTERNATIONAL JOURNAL OF MENTAL HEALTH PROMOTION.  24(5):679-697. 2022
• The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies.  BIOMEDICINE & PHARMACOTHERAPY.  153. 2022
• The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019.  LANCET.  400(10352):563-591. 2022
• The rs483145 polymorphism of MC4R gene is not associated with obesity in the Chilean population: Results of GENADIO study.  ENDOCRINOLOGIA DIABETES Y NUTRICION.  69(4):254-261. 2022
• Walking pace and cognitive impairment in elderly: finding from the Chilean National Health Survey 2016-2017.  SALUD UNINORTE.  38(3):819-836. 2022
• 5-Dodecanolide, a Compound Isolated from Pig Lard, Presents Powerful Anti-Inflammatory Properties.  MOLECULES.  26(23). 2021
• Acute Effect of Chili Consumption on Thermogenesis and Glycemic Response Following Oral Glucose Load in Men.  CURRENT TOPICS IN NUTRACEUTICAL RESEARCH.  19(3):288-294. 2021
• Amentoflavone, New Hope against SARS-CoV-2: An Outlook through its Scientific Records and an in silico Study.  PHARMACOGNOSY RESEARCH.  13(3):149-157. 2021
• Association between physical activity and income levels in chilean adults.  REVISTA MEDICA DE CHILE.  149(10):1450-1458. 2021
• Association of adiposity and diabetes mellitus type 2 by education level in the Chilean population.  REVISTA MEDICA DE CHILE.  149(6):819-828. 2021
• Development and antioxidant characterization of Ginger-Mint drink prepared through different extraction techniques.  JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION.  1-15. 2021
• Factors associated with depression in Chilean adults. Results of the 2016-2017 National Health Survey.  REVISTA MEDICA DE CHILE.  149(10):1430-1439. 2021
• Genetic variants in the SLC16A11 gene are associated with increased BMI and insulin levels in nondiabetic Chilean population.  ARCHIVES OF ENDOCRINOLOGY METABOLISM.  65(3):305-314. 2021
• Legume consumption in chileans: findings from the 2016-2017 national health survey.  REVISTA MEDICA DE CHILE.  149(5):698-707. 2021
• Number of years with type 2 diabetes is associated with suspicion of cognitive impairment in Chilean older adults: A cross-sectional study.  REVISTA ESPANOLA DE NUTRICION HUMANA Y DIETETICA.  25(3):316-325. 2021
• Pharmacological Activities of Crinum viviparum: A Laboratory-based Study.  JOURNAL OF HERBS, SPICES AND MEDICINAL PLANTS.  27(2):177-187. 2021
• Protective effect of Bridelia tomentosa due to its phenolic acids and flavonoids against oxidative stress-mediated hepatic toxicity induced by carbofuran.  SOUTH AFRICAN JOURNAL OF BOTANY.  141:447-456. 2021
• The FTO rs17817449 Polymorphism is Not Associated With Sedentary Time, Physical Activity, or Cardiorespiratory Fitness: Findings From the GENADIO Cross-Sectional Study.  JOURNAL OF PHYSICAL ACTIVITY & HEALTH.  18(11):1352-1357. 2021
• Water intake in the Chilean population: Findings from the 2016-17 National Health Survey.  REVISTA MEDICA DE CHILE.  149(1):52-61. 2021
• Antitumor Effects of Triterpenes in Hepatocellular Carcinoma.  CURRENT MEDICINAL CHEMISTRY.  1-20. 2020
• Ascorbic acid interaction with phytol: a modulatory effects on the anti-pyretic activity of paracetamol in Swiss albino mice.  CLINICAL PHYTOSCIENCE.  6. 2020
• Association between Walking Pace and Diabetes: Findings from the Chilean National Health Survey 2016-2017.  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH.  17(15). 2020
• Association of menopause with cardiovascular risk. Analysis of data from the 2016-17 Chilean national health survey.  REVISTA MEDICA DE CHILE.  148(2):178-186. 2020
• Calorie restriction improves physical performance and modulates the antioxidant and inflammatory responses to acute exercise.  NUTRIENTS.  12(4). 2020
• Changes of physical activity and ultra-processed food consumption in adolescents from different countries during covid-19 pandemic: An observational study.  NUTRIENTS.  12(8). 2020
• Chemical composition, adulteration, total microbial load, and heavy metal in raw milk samples collected from dairy farms and urban areas in lahore district, Pakistan.  JOURNAL OF FOOD SAFETY.  40(1):1-10. 2020
• Comparison between self-reported and device measured physical activity according to nutritional status.  REVISTA MEDICA DE CHILE.  148(1):37-45. 2020
• Comparison of self-reported and accelerometer-measured physical activity according to sociodemographic factors.  REVISTA CHILENA DE NUTRICION.  47(4):620-629. 2020
• Covid-19 confinement and changes of adolescent's dietary trends in Italy, Spain, Chile, Colombia and Brazil.  NUTRIENTS.  12(6). 2020
• Effect of free fatty acids on inflammatory gene expression and hydrogen peroxide production by ex vivo blood mononuclear cells.  NUTRIENTS.  12(1):1-13. 2020
• High-performance thin-layer chromatography fingerprinting, total phenolic and total flavonoid contents and anti-platelet-aggregation activities of Prosopis farcta extracts.  CELLULAR AND MOLECULAR BIOLOGY.  64(4):8-14. 2020
• Is waist-to-height ratio a better predictor of hypertension and type 2 diabetes than body mass index and waist circumference in the Chilean population?.  NUTRITION.  79-80. 2020
• Lifestyles and adherence to the Chilean Dietary Guidelines: results of the Chilean National Health 2016-2017 Survey.  REVISTA CHILENA DE NUTRICION.  47(4):650-657. 2020
• Older People in Chile: the new social, economic and health challenge for the 21th century.  REVISTA MEDICA DE CHILE.  148(6):799-809. 2020
• Physical activity and sedentary behaviors among people with cancer.  REVISTA MEDICA DE CHILE.  148(2):168-177. 2020
• Phytochemical screening of Alstonia scholaris eaf and bark extracts and their antimicrobial activities.  CELLULAR AND MOLECULAR BIOLOGY.  66(4):270-279. 2020
• Phytochemical screening of Alstonia venenata leaf and bark extracts and their antimicrobial activities.  CELLULAR AND MOLECULAR BIOLOGY.  66(4):224-231. 2020
• Phytochemical screening of Moringa oleifera leaf extracts and their antimicrobial activities.  CELLULAR AND MOLECULAR BIOLOGY.  66(1):20-26. 2020
• Prevalence of frailty among Chilean older people.  REVISTA MEDICA DE CHILE.  148(10):1418-1426. 2020
• Sociodemographic Patterning of Cardiorespiratory Fitness Derived by Equation in the Chilean Population: Findings from the Chilean Health Survey 2016-2017.  REVISTA MEDICA DE CHILE.  148(12):1750-1758. 2020
• Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health.  ACS OMEGA.  5(20):11849-11872. 2020
• Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications.  FRONTIERS IN PHARMACOLOGY.  11. 2020
• Untargeted profiling of field cultivated bush tea (Athrixia phylicoides DC.) based on metabolite analysis.  CELLULAR AND MOLECULAR BIOLOGY.  66(4):104-109. 2020
• Association between adiposity levels and cognitive impairment in the Chilean older adult population .  JOURNAL OF NUTRITIONAL SCIENCE.  8:1-8. 2019
• Association between sleep duration and cognitive impairment in older people.  REVISTA MEDICA DE CHILE.  147(11):1398-1406. 2019
• Association of rs3751812 polymorphism of the FTO gene with adiposity and metabolic markers in Chilean population. Results of the GENADIO study.  NUTRICION HOSPITALARIA.  36(3):589-598. 2019
• Occurrence and seasonal variations of aflatoxin M1 in milk from Punjab, Pakistan.  TOXINS.  11:1-15. 2019
• Physical activity and sedentary behaviours are associated with cognitive impairment in Chilean older adults.  REVISTA MEDICA DE CHILE.  147(10):1247-1255. 2019
• Association of a healthy lifestyle index with cardiovascular risk factors in Chileans adults.  REVISTA MEDICA DE CHILE.  146(12):1404-1415. 2018
• Association of the FTO (rs9939609) genotype with energy intake.  REVISTA MEDICA DE CHILE.  146(11):1252-1260. 2018
• Calorie restriction regime enhances physical performance of trained athletes.  JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION.  15:12:1-10. 2018
• Erythrocytes and Skeletal Muscle Unsaturated and Omega-6 Fatty Acids Are Positively Correlated after Caloric Restriction and Exercise.  ANNALS OF NUTRITION AND METABOLISM.  72(2):126-133. 2018
• Peripheral blood mononuclear cells antioxidant adaptations to regular physical activity in elderly people.  NUTRIENTS.  10(10):1-15. 2018
• Regular Practice of Moderate Physical Activity by Older Adults Ameliorates Their Anti-Inflammatory Status.  NUTRIENTS.  10(11):1-13. 2018
• Resolvins as proresolving inflammatory mediators in cardiovascular disease.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.  30:1-8. 2018
• Training and acute exercise modulates mitochondrial dynamics in football players' blood mononuclear cells.  EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY.  117(10):1977-1987. 2017
• Antioxidant Response of Chronic Wounds to Hyperbaric Oxygen Therapy.  PLOS ONE.  11(9):1-14. 2016
• Docosahexaenoic diet supplementation, exercise and temperature affect cytokine production by lipopolysaccharide-stimulated mononuclear cells.  JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY.  72(3):421-434. 2016
• Effects of Almond- and Olive Oil-Based Docosahexaenoic- and Vitamin E-Enriched Beverage Dietary Supplementation on Inflammation Associated to Exercise and Age.  NUTRIENTS.  8(10):1-18. 2016
• Effects of dietary Docosahexaenoic, training and acute exercise on lipid mediators.  JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION.  13(1):1-12. 2016
• Effects of dietary almond- and olive oil-based docosahexaenoic acid- and vitamin E-enriched beverage supplementation on athletic performance and oxidative stress markers.  FOOD & FUNCTION.  7(12):4920-4934. 2016
• Mediterranean diets supplemented with virgin olive oil and nuts enhance plasmatic antioxidant capabilities and decrease xanthine oxidase activity in people with metabolic syndrome: The PREDIMED study .  MOLECULAR NUTRITION & FOOD RESEARCH.  60(12):2654-2664. 2016
• No effect of acute beetroot juice ingestion on oxygen consumption, glucose kinetics, or skeletal muscle metabolism during submaximal exercise in males.  JOURNAL OF APPLIED PHYSIOLOGY.  120(4):391-398. 2016
• Training Enhances Immune Cells Mitochondrial Biosynthesis, Fission, Fusion, and Their Antioxidant Capabilities Synergistically with Dietary Docosahexaenoic Supplementation.  OXIDATIVE MEDICINE AND CELLULAR LONGEVITY.  2016:1-10. 2016
• Effects of Docosahexaenoic Supplementation and In Vitro Vitamin C on the Oxidative and Inflammatory neutrophil Response to Activation.  OXIDATIVE MEDICINE AND CELLULAR LONGEVITY.  2015:1-12. 2015